Metrological characterisation of micro-vesicles from body fluids

Welcome to the website of European Metrology Research Programme (EMRP) Joint Research Project (JRP) HLT02: Metrological characterisation of micro-vesicles from body fluids as non-invasive diagnostic biomarkers (METVES).

METVES impression
Human blood contains numerous cell-derived microvesicles (left). METVES combines state-of-the-art clinical and biochemical knowledge with advanced metrological techniques (center, right) to quantify - for the first time - clinically relevant properties of microvesicles as novel biomarkers of disease, thereby enabling earlier detection of common diseases, improving healthcare, and reducing the costs of health care.

This website contains the news items, a project summary, and a description of the work packages of the research project. In addition, you can find a list with the people and institutes involved, an overview of the generated output, upcoming events, and links relevant to the project. If you have any questions, please do not hesitate to contact us.

News

11 November 2015  Our manuscript on handling and storage of human body fluids for analysis of extracellular vesicles (pdf, 4,336 kB) is published in the Journal of Extracellular Vesicles.
21 October 2015  The final summary of the METVES project (pdf, 861 kB) is made available to download.
28 May 2015  METVES organizes a workshop on the Metrological Characterization of Microvesicles.
27 February 2015  Four videos with standard operation procedures of vesicle isolation and detection are placed on YouTube.
1 August 2014  The METVES report on the list of stakeholder requirements for the use of methods for dimensional characterisation of microvesicles in medical centres (pdf, 616 kB) is made available to download.
8 July 2014  Our manuscript on co-isolation of extracellular vesicles and high-density lipoproteins using density gradient ultracentrifugation (pdf, 798 kB) is accepted for publication in the Journal of Extracellular Vesicles.
25 April 2014  Our manuscript on the particle size distribution of exosomes and microvesicles by transmission electron microscopy, flow cytometry, nanoparticle tracking analysis, and resistive pulse sensing (pdf, 460 kB) is accepted for publication in the Journal of Thrombosis and Haemostasis.